MTHFD1L-Mediated Redox Homeostasis Promotes Tumor Progression in Tongue Squamous Cell Carcinoma

MTHFD1L-Mediated Redox Homeostasis Promotes Tumor Progression in Tongue Squamous Cell Carcinoma

Background: Routine changes in cell metabolism can drive tumor development, as the cellular program develops to promote glycolysis and redox homeostasis during tumor progression; however, the associated mechanisms in tongue squamous cell carcinoma (TSCC) remain unclear.Methods: We investigated methy...

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Bibliographic Details
Main Authors: Hao Li, Xiaoyan Fu, Fan Yao, Tian Tian, Chunyang Wang, Ankui Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
tongue squamous cell carcinoma
MTHFD1L expression
anti-oxidant activity
tumorigenesis
mTORC1
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01278/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01278/full

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