SETD2 mutations in primary central nervous system tumors

SETD2 mutations in primary central nervous system tumors

Abstract Mutations in SETD2 are found in many tumors, including central nervous system (CNS) tumors. Previous work has shown these mutations occur specifically in high grade gliomas of the cerebral hemispheres in pediatric and young adult patients. We investigated SETD2 mutations in a cohort of appr...

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Bibliographic Details
Main Authors: Angela N. Viaene, Mariarita Santi, Jason Rosenbaum, Marilyn M. Li, Lea F. Surrey, MacLean P. Nasrallah
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Acta Neuropathologica Communications
Subjects:
SETD2
Histone
Brain tumor
Glioma
Epigenetics
H3K36me3
Online Access:http://link.springer.com/article/10.1186/s40478-018-0623-0

Internet

http://link.springer.com/article/10.1186/s40478-018-0623-0

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