Exploring Animal Models That Resemble Idiopathic Pulmonary Fibrosis

Exploring Animal Models That Resemble Idiopathic Pulmonary Fibrosis

Large multicenter clinical trials have led to two recently approved drugs for patients with idiopathic pulmonary fibrosis (IPF); yet, both of these therapies only slow disease progression and do not provide a definitive cure. Traditionally, preclinical trials have utilized mouse models of bleomycin...

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Bibliographic Details
Main Authors: Jun Tashiro, Gustavo A. Rubio, Andrew H. Limper, Kurt Williams, Sharon J. Elliot, Ioanna Ninou, Vassilis Aidinis, Argyrios Tzouvelekis, Marilyn K. Glassberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Medicine
Subjects:
bleomycin
idiopathic pulmonary fibrosis
murine model
asbestosis
aged mice
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2017.00118/full

Internet

http://journal.frontiersin.org/article/10.3389/fmed.2017.00118/full

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