Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications

Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications

Adoptive cellular immunotherapy (ACT) employing engineered T lymphocytes expressing chimeric antigen receptors (CARs) has demonstrated promising antitumor effects in advanced hematologic cancers, such as relapsed or refractory acute lymphoblastic leukemia, chronic lymphocytic leukemia, and non-Hodgk...

Full description

Bibliographic Details
Main Authors: Hamid R. Mirzaei, Analiz Rodriguez, Jennifer Shepphird, Christine E. Brown, Behnam Badie
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
immunotherapy
T cell therapy
chimeric antigen receptor
CAR
solid tumors
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2017.01850/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2017.01850/full

Similar Items