Escherichia coli FtsA forms lipid-bound minirings that antagonize lateral interactions between FtsZ protofilaments

The actin-like protein FtsA and the tubulin-like protein FtsZ play crucial roles during cell division in most bacteria. Here, the authors show that FtsA forms minirings on lipid monolayers, and present evidence supporting that its oligomeric state modulates the bundling of FtsZ protofilaments.

Bibliographic Details
Main Authors: Marcin Krupka, Veronica W. Rowlett, Dustin Morado, Heidi Vitrac, Kara Schoenemann, Jun Liu, William Margolin
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15957