Inhibitory Effects of Epipolythiodioxopiperazine Fungal Metabolites on Isocitrate Lyase in the Glyoxylate Cycle of <i>Candida albicans</i>

Inhibitory Effects of Epipolythiodioxopiperazine Fungal Metabolites on Isocitrate Lyase in the Glyoxylate Cycle of <i>Candida albicans</i>

Four epipolythiodioxopiperazine fungal metabolites (<b>1</b>–<b>4</b>) isolated from the sponge-derived <i>Aspergillus quadrilineatus</i> FJJ093 were evaluated for their capacity to inhibit isocitrate lyase (ICL) in the glyoxylate cycle of <i>Candida albican...

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Bibliographic Details
Main Authors: Ji-Yeon Hwang, Beomkoo Chung, Oh-Seok Kwon, Sung Chul Park, Eunji Cho, Dong-Chan Oh, Jongheon Shin, Ki-Bong Oh
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Marine Drugs
Subjects:
epipolythiodioxopiperazines
sponge-derived fungus
<i>Aspergillus quadrilineatus</i>
<i>Candida albicans</i>
isocitrate lyase
Online Access:https://www.mdpi.com/1660-3397/19/6/295

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https://www.mdpi.com/1660-3397/19/6/295

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