N-quinoline-benzenesulfonamide derivatives exert potent anti-lymphoma effect by targeting NF-κB

N-quinoline-benzenesulfonamide derivatives exert potent anti-lymphoma effect by targeting NF-κB

Summary: We previously identified the N-quinoline-benzenesulfonamide (NQBS) scaffold as a potent inhibitor of nuclear factor-κB (NF-κB) translocation. Now, we report the structure-activity relationship of compounds with the NQBS scaffold in models of diffuse large B-cell lymphoma (DLBCL). We identif...

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Bibliographic Details
Main Authors: Matko Kalac, Michael Mangone, Alison Rinderspacher, Shi-Xian Deng, Luigi Scotto, Michael Markson, Mukesh Bansal, Andrea Califano, Donald W. Landry, Owen A. O'Connor
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:iScience
Subjects:
Chemistry
Medical Biochemistry
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220310816

Internet

http://www.sciencedirect.com/science/article/pii/S2589004220310816

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