Nudel and FAK as antagonizing strength modulators of nascent adhesions through paxillin.
Adhesion and detachment are coordinated critical steps during cell migration. Conceptually, efficient migration requires both effective stabilization of membrane protrusions at the leading edge via nascent adhesions and their successful persistence during retraction of the trailing side via disrupti...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-05-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC2684528?pdf=render |