Improved cartilage regeneration by implantation of acellular biomaterials after bone marrow stimulation: a systematic review and meta-analysis of animal studies

Microfracture surgery may be applied to treat cartilage defects. During the procedure the subchondral bone is penetrated, allowing bone marrow-derived mesenchymal stem cells to migrate towards the defect site and form new cartilage tissue. Microfracture surgery generally results in the formation of...

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Bibliographic Details
Main Authors: Michiel W. Pot, Veronica K. Gonzales, Pieter Buma, Joanna IntHout, Toin H. van Kuppevelt, Rob B.M. de Vries, Willeke F. Daamen
Format: Article
Language:English
Published: PeerJ Inc. 2016-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/2243.pdf