Stromal Derived Factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis

<p>Abstract</p> <p>Renal cell carcinoma (RCC) is characterized by organ-specific metastases. The chemokine stromal derived factor-1 (SDF-1/CXCL12) and its receptor CXCR4 have been suggested to regulate organ-specific metastasis in various other cancers. On this basis, we hypothesiz...

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Bibliographic Details
Main Authors: Reckamp Karen, Thomas George V, Phillips Roderick J, Burdick Marie D, Mestas Javier, Pan Judong, Belperio John A, Strieter Robert M
Format: Article
Language:English
Published: BMC 2006-11-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/56