Application of WES Towards Molecular Investigation of Congenital Cataracts: Identification of Novel Alleles and Genes in a Hospital-Based Cohort of South India

Application of WES Towards Molecular Investigation of Congenital Cataracts: Identification of Novel Alleles and Genes in a Hospital-Based Cohort of South India

Congenital cataracts are the prime cause for irreversible blindness in children. The global incidence of congenital cataract is 2.2–13.6 per 10,000 births, with the highest prevalence in Asia. Nearly half of the congenital cataracts are of familial nature, with a predominant autosomal dominant patte...

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Bibliographic Details
Main Authors: Dinesh Kumar Kandaswamy, Makarla Venkata Sathya Prakash, Jochen Graw, Samuel Koller, István Magyar, Amit Tiwari, Wolfgang Berger, Sathiyaveedu Thyagarajan Santhiya
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
congenital cataract
WES
FYCO1
PAX6
EPHA2
P3H2
Online Access:https://www.mdpi.com/1422-0067/21/24/9569

Internet

https://www.mdpi.com/1422-0067/21/24/9569

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