The Fractalkine Receptor CX3CR1 Links Lymphocyte Kinetics in CMV-Seropositive Patients and Acute Myocardial Infarction With Adverse Left Ventricular Remodeling

The Fractalkine Receptor CX3CR1 Links Lymphocyte Kinetics in CMV-Seropositive Patients and Acute Myocardial Infarction With Adverse Left Ventricular Remodeling

AimsLatent cytomegalovirus (CMV) infection is associated with adverse cardiovascular outcomes. Virus-specific CX3CR1+ effector memory T-cells may be instrumental in this process due to their pro-inflammatory properties. We investigated the role of CX3CR1 (fractalkine receptor) in CMV-related lymphoc...

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Bibliographic Details
Main Authors: Luke Spray, Catherine Park, Suzanne Cormack, Ashfaq Mohammed, Pedram Panahi, Stephen Boag, Karim Bennaceur, Kateryna Sopova, Gavin Richardson, Verena M. Stangl, Lavinia Rech, Peter P. Rainer, Gustavo Campos Ramos, Ulrich Hofmann, Konstantinos Stellos, Ioakim Spyridopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
acute myocardial infarction
CX3CR1
cytomegalovirus
cardiac MRI
remodeling
T-lymphocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.605857/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.605857/full

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