Report on a large animal study with Göttingen Minipigs where regenerates and controls for articular cartilage were created in a large number. Focus on the conditions of the operated stifle joints and suggestions for standardized procedures.

The characterization of regenerated articular cartilage (AC) can be based on various methods, as there is an unambiguous accepted criterion neither for the natural cartilage tissue nor for regenerates. Biomechanical aspects should be considered as well, leading to the need for more equivalent sample...

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Bibliographic Details
Main Authors: Markus L Schwarz, Gregor Reisig, Andy Schütte, Kristianna Becker, Susanne Serba, Elmar Forsch, Steffen Thier, Stefan Fickert, Tamara Lenz, Christel Weiß, Svetlana Hetjens, Frederic Bludau, Friederike Bothe, Wiltrud Richter, Barbara Schneider-Wald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224996