Activation of invariant NKT cells exacerbates experimental visceral leishmaniasis.

Activation of invariant NKT cells exacerbates experimental visceral leishmaniasis.

We report that natural killer T (NKT) cells play only a minor physiological role in protection from Leishmania donovani infection in C57BL/6 mice. Furthermore, attempts at therapeutic activation of invariant NKT (iNKT) cells with alpha-galactosylceramide (alpha-GalCer) during L. donovani infection e...

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Bibliographic Details
Main Authors: Amanda C Stanley, Yonghong Zhou, Fiona H Amante, Louise M Randall, Ashraful Haque, Daniel G Pellicci, Geoff R Hill, Mark J Smyth, Dale I Godfrey, Christian R Engwerda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2265425?pdf=render

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http://europepmc.org/articles/PMC2265425?pdf=render

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