<it>O</it><sup><it>6</it></sup>-<it>methylguanine-DNA methyltransferase </it>is downregulated in transformed astrocyte cells: implications for anti-glioma therapies
<p>Abstract</p> <p>Background</p> <p>A novel alkylating agent, temozolomide, has proven efficacious in the treatment of malignant gliomas. However, expression of <it>O</it><sup><it>6</it></sup><it>-methylguanine-DNA methyltransf...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2007-06-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/6/1/36 |