The baseline interferon signature predicts disease severity over the subsequent 5 years in systemic lupus erythematosus

The baseline interferon signature predicts disease severity over the subsequent 5 years in systemic lupus erythematosus

Abstract Objectives Type I interferons (IFNs) play an important role in the pathophysiology of systemic lupus erythematosus (SLE). While cross-sectional data suggest an association between IFN-induced gene expression and SLE disease activity, interest in this as a biomarker of flare has been tempere...

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Bibliographic Details
Main Authors: Lloyd Mai, Arundip Asaduzzaman, Babak Noamani, Paul R. Fortin, Dafna D. Gladman, Zahi Touma, Murray B. Urowitz, Joan Wither
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Arthritis Research & Therapy
Subjects:
Systemic lupus erythematosus
Interferon
Disease course
SLEDAI-2K
Online Access:https://doi.org/10.1186/s13075-021-02414-0

Internet

https://doi.org/10.1186/s13075-021-02414-0

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