The Specificity of Downstream Signaling for A<sub>1</sub> and A<sub>2A</sub>R Does Not Depend on the C-Terminus, Despite the Importance of This Domain in Downstream Signaling Strength

The Specificity of Downstream Signaling for A<sub>1</sub> and A<sub>2A</sub>R Does Not Depend on the C-Terminus, Despite the Importance of This Domain in Downstream Signaling Strength

Recent efforts to determine the high-resolution crystal structures for the adenosine receptors (A<sub>1</sub>R and A<sub>2A</sub>R) have utilized modifications to the native receptors in order to facilitate receptor crystallization and structure determination. One common modi...

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Bibliographic Details
Main Authors: Abhinav R. Jain, Claire McGraw, Anne S. Robinson
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biomedicines
Subjects:
yeast pheromone response
G protein-coupled receptors
adenosine receptor
C-terminus
G protein
receptor chimera
Online Access:https://www.mdpi.com/2227-9059/8/12/603

Internet

https://www.mdpi.com/2227-9059/8/12/603

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