NONO promotes hepatocellular carcinoma progression by enhancing fatty acids biosynthesis through interacting with ACLY mRNA

NONO promotes hepatocellular carcinoma progression by enhancing fatty acids biosynthesis through interacting with ACLY mRNA

Abstract Background Dysregulation of fatty acid (FA) metabolism is involved in hepatocellular carcinoma (HCC) development. Non-POU domain-containing octamer binding protein (NONO), known as the component of nuclear paraspeckles, has recently been found to promote HCC progression. In this study, we i...

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Bibliographic Details
Main Authors: Hongda Ding, Junpeng Liu, Caibin Wang, Yang Su
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Cancer Cell International
Subjects:
Hepatocellular carcinoma
Non-POU domain-containing octamer binding protein
Fatty acid biosynthesis
ATP-citrate lyase
Insulin like growth factor 2 mRNA binding protein 1
Online Access:http://link.springer.com/article/10.1186/s12935-020-01520-4

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http://link.springer.com/article/10.1186/s12935-020-01520-4

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