Can Electronic Health Records Databases Complement Spontaneous Reporting System Databases? A Historical-Reconstruction of the Association of Rofecoxib and Acute Myocardial Infarction

Can Electronic Health Records Databases Complement Spontaneous Reporting System Databases? A Historical-Reconstruction of the Association of Rofecoxib and Acute Myocardial Infarction

Background: Several initiatives have assessed if mining electronic health records (EHRs) may accelerate the process of drug safety signal detection. In Europe, Exploring and Understanding Adverse Drug Reactions (EU-ADR) Project Focused on utilizing clinical data from EHRs of over 30 million patients...

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Bibliographic Details
Main Authors: Vaishali K. Patadia, Martijn J. Schuemie, Preciosa M. Coloma, Ron Herings, Johan van der Lei, Miriam Sturkenboom, Gianluca Trifirò
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
EU-ADR
WHO-VigiBase
signal detection
EHR
LGPS
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00594/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00594/full

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