Anti-Nogo-A immunotherapy does not alter hippocampal neurogenesis after stroke in adult rats

Ischemic stroke is a leading cause of adult disability, including cognitive impairment. Our laboratory has previously shown that treatment with function-blocking antibodies against the neurite growth inhibitory protein Nogo-A promotes functional recovery after stroke in adult and aged rats, includi...

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Bibliographic Details
Main Authors: Daniel J. Shepherd, Shih-Yen Tsai, Timothy E. O'Brien, Robert G. Farrer, Gwendolyn L. Kartje
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00467/full