Gene Expression of Protein Tyrosine Phosphatase 1B and Endoplasmic Reticulum Stress During Septic Shock

Gene Expression of Protein Tyrosine Phosphatase 1B and Endoplasmic Reticulum Stress During Septic Shock

Introduction: Protein Tyrosine Phosphatase 1B (PTP1B) and endoplasmic reticulum stress (ERS) are involved in the septic inflammatory response. Their inhibition is associated with improved survival in murine models of sepsis. The objective was to describe PTP1B and ERS expression during septic shock...

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Bibliographic Details
Main Authors: Thomas Clavier, Steven Grangé, Thibaut Pressat-Laffouilhere, Emmanuel Besnier, Sylvanie Renet, Sylvain Fraineau, Pierre-Alain Thiebaut, Vincent Richard, Benoit Veber, Fabienne Tamion
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Medicine
Subjects:
protein tyrosine phosphatase
non-receptor type 1/metabolism
endoplasmic reticulum stress
sepsis
shock
endothelium
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2019.00240/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2019.00240/full

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