Mitochondrial proteomic profile of complex IV deficiency fibroblasts: rearrangement of oxidative phosphorylation complex/supercomplex and other metabolic pathways

Mitochondrial proteomic profile of complex IV deficiency fibroblasts: rearrangement of oxidative phosphorylation complex/supercomplex and other metabolic pathways

Background: Mitochondriopathies are multisystem diseases affecting the oxidative phosphorylation (OXPHOS) system. Skin fibroblasts are a good model for the study of these diseases. Fibroblasts with a complex IV mitochondriopathy were used to determine the molecular mechanism and the main affected fu...

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Bibliographic Details
Main Authors: Karina Salvador-Severo, Leopoldo Gómez-Caudillo, Héctor Quezada, José de Jesús García-Trejo, Alan Cárdenas-Conejo, Martha Elisa Vázquez-Memije, Fernando Minauro-Sanmiguel
Format: Article
Language:English
Published: Permanyer 2017-05-01
Series:Boletín Médico del Hospital Infantil de México
Subjects:
Mitochondriopathy
Respiratory complex
Oxidative phosphorylation (OXPHOS)
Proteome
Online Access:http://www.sciencedirect.com/science/article/pii/S1665114617300497

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http://www.sciencedirect.com/science/article/pii/S1665114617300497

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