Single-Molecule, Super-Resolution, and Functional Analysis of G Protein-Coupled Receptor Behavior Within the T Cell Immunological Synapse

Single-Molecule, Super-Resolution, and Functional Analysis of G Protein-Coupled Receptor Behavior Within the T Cell Immunological Synapse

A central process in immunity is the activation of T cells through interaction of T cell receptors (TCRs) with agonistic peptide-major histocompatibility complexes (pMHC) on the surface of antigen presenting cells (APCs). TCR-pMHC binding triggers the formation of an extensive contact between the tw...

Full description

Bibliographic Details
Main Authors: James H. Felce, Lucia Parolini, Erdinc Sezgin, Pablo F. Céspedes, Kseniya Korobchevskaya, Mathew Jones, Yanchun Peng, Tao Dong, Marco Fritzsche, Dirk Aarts, John Frater, Michael L. Dustin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
lymphocyte
synapse
fluorescence
microscopy
receptor
tracking
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.608484/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.608484/full

Similar Items