Oxysterol binding protein-related protein 8 mediates the cytotoxicity of 25-hydroxycholesterol[S]

Oxysterols are 27-carbon oxidized derivatives of cholesterol or by-products of cholesterol biosynthesis that can induce cell apoptosis in addition to a number of other bioactions. However, the mechanisms underlying this cytotoxicity are not completely understood. ORP8 is a member of the oxysterol bi...

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Bibliographic Details
Main Authors: Jiwei Li, Xiuting Zheng, Ning Lou, Wenbin Zhong, Daoguang Yan
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520353931