Concordance of CSF measures of Alzheimer's pathology with amyloid PET status in a preclinical cohort: A comparison of Lumipulse and established immunoassays

Concordance of CSF measures of Alzheimer's pathology with amyloid PET status in a preclinical cohort: A comparison of Lumipulse and established immunoassays

Abstract Introduction We assessed the concordance of cerebrospinal fluid (CSF) amyloid beta (Aβ) and tau measured on the fully automated Lumipulse platform with pre‐symptomatic Alzheimer's disease (AD) pathology on amyloid positron emission tomography (PET). Methods In 72 individuals from the I...

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Bibliographic Details
Main Authors: Ashvini Keshavan, Henrietta Wellington, Zhongbo Chen, Ayesha Khatun, Miles Chapman, Melanie Hart, David M. Cash, William Coath, Thomas D. Parker, Sarah M. Buchanan, Sarah E. Keuss, Matthew J. Harris, Heidi Murray‐Smith, Amanda Heslegrave, Nick C. Fox, Henrik Zetterberg, Jonathan M. Schott
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
amyloid
CSF
Lumipulse
PET
tau
Online Access:https://doi.org/10.1002/dad2.12097

Internet

https://doi.org/10.1002/dad2.12097

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