Cyanidin-3-O-glucoside attenuates amyloid-beta (1–40)-induced oxidative stress and apoptosis in SH-SY5Y cells through a Nrf2 mechanism

Cyanidin-3-O-glucoside attenuates amyloid-beta (1–40)-induced oxidative stress and apoptosis in SH-SY5Y cells through a Nrf2 mechanism

Scope: We investigated the cytoprotective effects of cyanidin-3-O-glucoside (C3G) against oxidative stress and apoptosis induced by beta-amyloid1-40 (Aβ1-40) in SH-SY5Y cells. Methods and results: We measured intracellular reactive oxygen species (ROS) with fluorescent marker DCFH2-DA, superoxide di...

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Bibliographic Details
Main Authors: Ling-shuai Meng, Bin Li, Dong-nan Li, Yue-hua Wang, Yang Lin, Xian-jun Meng, Xi-yun Sun, Ning Liu
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Journal of Functional Foods
Subjects:
Cyanidin-3-O-glucoside
SH-SY5Y cell
Aβ1-40
Oxidative stress
Apoptosis
NrF2/ARE activation
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617305376

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http://www.sciencedirect.com/science/article/pii/S1756464617305376

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