The calcium binding protein S100β marks hedgehog-responsive resident vascular stem cells within vascular lesions

The calcium binding protein S100β marks hedgehog-responsive resident vascular stem cells within vascular lesions

Abstract A hallmark of subclinical atherosclerosis is the accumulation of vascular smooth muscle cell (SMC)-like cells leading to intimal thickening. While medial SMCs contribute, the participation of hedgehog-responsive resident vascular stem cells (vSCs) to lesion formation remains unclear. Using...

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Bibliographic Details
Main Authors: Mariana Di Luca, Emma Fitzpatrick, Denise Burtenshaw, Weimin Liu, Jay-Christian Helt, Roya Hakimjavadi, Eoin Corcoran, Yusof Gusti, Daniel Sheridan, Susan Harman, Catriona Lally, Eileen M. Redmond, Paul A. Cahill
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00120-8

Internet

https://doi.org/10.1038/s41536-021-00120-8

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