Turnera diffusa extract attenuates profibrotic, extracellular matrix and mitochondrial markers in activated human hepatic stellate cells (HSC)

Introduction and objectives: Hepatic fibrosis is characterized by the accumulation of extracellular matrix which includes the accumulation of α-smooth muscle actin (α-SMA), collagen type I (COL1α1), as well as remodeling induced by metalloproteinases and tissue inhibitor of metalloproteinase (TIMPs)...

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Bibliographic Details
Main Authors: Diana Raquel Rodríguez-Rodríguez, Sonia Amelia Lozano-Sepulveda, Cecilia Delgado-Montemayor, Noemí Waksman, Paula Cordero-Perez, Ana María Rivas-Estilla
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268120302064