Microbiota influence the development of the brain and behaviors in C57BL/6J mice.

We investigated the contributions of commensal bacteria to brain structural maturation by magnetic resonance imaging and behavioral tests in four and 12 weeks old C57BL/6J specific pathogen free (SPF) and germ free (GF) mice. SPF mice had increased volumes and fractional anisotropy in major gray and...

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Bibliographic Details
Main Authors: Jing Lu, Sylvia Synowiec, Lei Lu, Yueyue Yu, Talitha Bretherick, Silvia Takada, Vasily Yarnykh, Jack Caplan, Michael Caplan, Erika C Claud, Alexander Drobyshevsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6075787?pdf=render