To achieve an earlier IFN-γ response is not sufficient to control Mycobacterium tuberculosis infection in mice.

The temporo-spatial relationship between the three organs (lung, spleen and lymph node) involved during the initial stages of Mycobacterium tuberculosis infection has been poorly studied. As such, we performed an experimental study to evaluate the bacillary load in each organ after aerosol or intrav...

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Bibliographic Details
Main Authors: Cristina Vilaplana, Clara Prats, Elena Marzo, Carles Barril, Marina Vegué, Jorge Diaz, Joaquim Valls, Daniel López, Pere-Joan Cardona
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4069189?pdf=render