Frequent Loss of TIMP-3 Expression in Progression of Esophageal and Gastric Adenocarcinomas

Frequent Loss of TIMP-3 Expression in Progression of Esophageal and Gastric Adenocarcinomas

Tissue inhibitor of metalloproteinase 3 (TIMP-3) promoter methylation has been linked to loss of TIMP-3 expression in various cancers. In this study, we analyzed TIMP-3 gene methylation using MethyLight assay and TIMP-3 mRNA expression using reverse transcription–polymerase chain reaction analysis...

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Main Authors: Ping Gu, Xiangbin Xing, Marc Tänzer, Christoph Röcken, Wilko Weichert, Audrius Ivanauskas, Matthias Pross, Ulrich Peitz, Peter Malfertheiner, Roland M. Schmid, Matthias P.A. Ebert
Format: Article
Language:English
Published: Elsevier 2008-06-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608801455

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http://www.sciencedirect.com/science/article/pii/S1476558608801455

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