DNA methylation dynamic of bone marrow hematopoietic stem cells after allogeneic transplantation

DNA methylation dynamic of bone marrow hematopoietic stem cells after allogeneic transplantation

Abstract Background Allogeneic hematopoietic stem cell transplantation (AHSCT) is a curative therapeutic approach for different hematological malignancies (HMs), and epigenetic modifications, including DNA methylation, play a role in the reconstitution of the hematopoietic system after AHSCT. This s...

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Bibliographic Details
Main Authors: Stefania Trino, Pietro Zoppoli, Angelo Michele Carella, Ilaria Laurenzana, Alessandro Weisz, Domenico Memoli, Giovanni Calice, Francesco La Rocca, Vittorio Simeon, Lucia Savino, Luigi Del Vecchio, Pellegrino Musto, Antonella Caivano, Luciana De Luca
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Stem Cell Research & Therapy
Subjects:
Allogeneic hematopoietic bone marrow stem cell transplantation
Hematopoietic stem and progenitor cells
DNA methylation
CpG sites
Hematological malignancies
Promoter methylation region
Online Access:http://link.springer.com/article/10.1186/s13287-019-1245-6

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http://link.springer.com/article/10.1186/s13287-019-1245-6

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