Next-Generation Sequencing at High Sequencing Depth as a Tool to Study the Evolution of Metastasis Driven by Genetic Change Events of Lung Squamous Cell Carcinoma

Next-Generation Sequencing at High Sequencing Depth as a Tool to Study the Evolution of Metastasis Driven by Genetic Change Events of Lung Squamous Cell Carcinoma

Background: The aim of this study is to report tumoral genetic mutations observed at high sequencing depth in a lung squamous cell carcinoma (SqCC) sample. We describe the findings and differences in genetic mutations that were studied by deep next-generation sequencing methods on the primary tumor...

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Bibliographic Details
Main Authors: Hicham Mansour, Abdelhak Ouhajjou, Vladimir B. Bajic, Roberto Incitti
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
lung cancer
NGS
FGFR
HRAS
CDKN2
tumor evolution
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01215/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01215/full

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