The core Cas1 protein of CRISPR-Cas I-B in Leptospira shows metal-tunable nuclease activity

The core Cas1 protein of CRISPR-Cas I-B in Leptospira shows metal-tunable nuclease activity

Leptospira interrogans serovar Copenhageni strain Fiocruz L1-130 is the causative agent of leptospirosis in animals and humans. This organism carries a functional cas1 gene classified under CRISPR-Cas I-B. In this study, using various nuclease assays and bioinformatics analysis, we report that the r...

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Bibliographic Details
Main Authors: Bhuvan Dixit, Aman Prakash, Pankaj Kumar, Prerana Gogoi, Manish Kumar
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Current Research in Microbial Sciences
Subjects:
Leptospira
Nucleases
Cas protein
CRISPR-Cas
DNase
Online Access:http://www.sciencedirect.com/science/article/pii/S2666517421000407

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http://www.sciencedirect.com/science/article/pii/S2666517421000407

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