The core Cas1 protein of CRISPR-Cas I-B in Leptospira shows metal-tunable nuclease activity
Leptospira interrogans serovar Copenhageni strain Fiocruz L1-130 is the causative agent of leptospirosis in animals and humans. This organism carries a functional cas1 gene classified under CRISPR-Cas I-B. In this study, using various nuclease assays and bioinformatics analysis, we report that the r...
Main Authors: | Bhuvan Dixit, Aman Prakash, Pankaj Kumar, Prerana Gogoi, Manish Kumar |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-12-01
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Series: | Current Research in Microbial Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666517421000407 |
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