Severe Wegener's granulomatosis successfully treated with rituximab

Severe Wegener's granulomatosis successfully treated with rituximab

The paper discusses the problems of the diagnosis and treatment of Wegener's granulomatosis, the most common anti-neutrophil cytoplasmic antibody-associated systemic vasculitis. It describes a clinical case in which the administration of rituximab could achieve remission of severe Wegener'...

Full description

Bibliographic Details
Main Authors: E N Semenkova, O G Krivosheyev, P I Novikov, V I Osipenko, N R Nosova, S A Parfenova, N V Nikiforova, O O Borodin
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2010-06-01
Series:Терапевтический архив
Subjects:
wegener's granulomatosis
renal lesion
refractory course
rituximab
Online Access:https://ter-arkhiv.ru/0040-3660/article/view/30630
Description
Summary:The paper discusses the problems of the diagnosis and treatment of Wegener's granulomatosis, the most common anti-neutrophil cytoplasmic antibody-associated systemic vasculitis. It describes a clinical case in which the administration of rituximab could achieve remission of severe Wegener's granulomatosis in a young man having numerous adverse reactions associated with the long-term use of high- and average-dose glucocorticoids and nonselective immunosuppressive agents. A place of rituximab in current drug therapy for Wegener's granulomatosis is shown.
ISSN:0040-3660
2309-5342

Similar Items