Genetic variation of the Fc gamma receptor 3B gene and association with rheumatoid arthritis.

<h4>Background</h4>Fc gamma receptors (FcγRs) play a crucial role in immunity by linking IgG antibody-mediated responses with cellular effector and regulatory functions. Genetic variants in these receptors have been previously identified as risk factors for several chronic inflammatory c...

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Main Authors: Rute B Marques, Mohamed M Thabet, Stefan J White, Jeanine J Houwing-Duistermaat, Aleida M Bakker, Gert-Jan Hendriks, Alexandra Zhernakova, Tom W Huizinga, Annette H van der Helm-van Mil, Rene E Toes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20957197/?tool=EBI