Rosiglitazone (BRL49653), a PPARγ-selective agonist, causes peroxisome proliferator-like liver effects in obese mice

Rosiglitazone (BRL49653), a PPARγ-selective agonist, causes peroxisome proliferator-like liver effects in obese mice

The PPAR (peroxisome proliferator activated receptor) transcription factors are ligand-activated nuclear receptors that regulate genes involved in lipid metabolism and homeostasis. PPARα is preferentially expressed in liver and PPARγ preferentially in adipose tissue. Activation of PPARα leads to per...

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Bibliographic Details
Main Authors: Ulrika Edvardsson, Monica Bergström, Maria Alexandersson, Krister Bamberg, Bengt Ljung, Björn Dahllöf
Format: Article
Language:English
Published: Elsevier 1999-07-01
Series:Journal of Lipid Research
Subjects:
BRL49653
WY14,643
peroxisome proliferation
PPAR
proteomics
ob/ob
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520334799

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http://www.sciencedirect.com/science/article/pii/S0022227520334799

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