Preparation and characterization of pelletized solid dispersion of resveratrol with mesoporous silica microparticles to improve dissolution by fluid-bed coating techniques

With hydrophilic surface and high surface area, porous silica has been applied to load insoluble drugs. Compared to solvent equilibrium method, resveratrol (RES)–mesoporous silica microparticles (MSM) solid dispersion prepared by fluid bed demonstrated higher drug loading and more complete dissoluti...

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Bibliographic Details
Main Authors: Jian Li, Xiaoqing Miao, Tongkai Chen, Defang Ouyang, Ying Zheng
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087615001300