Immune checkpoint molecules B7-H6 and PD-L1 co-pattern the tumor inflammatory microenvironment in human breast cancer

Immune checkpoint molecules B7-H6 and PD-L1 co-pattern the tumor inflammatory microenvironment in human breast cancer

Abstract B7-H6 and PD-L1 belong to the B7 family co-stimulatory molecules fine-tuning the immune response. The present work investigates the clinical effect of B7-H6 protein expression with PD-L1 status and the infiltration of natural killer cells as potential biomarkers in breast tumor inflammatory...

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Bibliographic Details
Main Authors: Boutheina Cherif, Hana Triki, Slim Charfi, Lobna Bouzidi, Wala Ben Kridis, Afef Khanfir, Kais Chaabane, Tahya Sellami-Boudawara, Ahmed Rebai
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87216-9

Internet

https://doi.org/10.1038/s41598-021-87216-9

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