The Oncogenic Signaling Pathways in <i>BRAF</i>-Mutant Melanoma Cells Are Modulated by Naphthalene Diimide-Like G-Quadruplex Ligands

The Oncogenic Signaling Pathways in <i>BRAF</i>-Mutant Melanoma Cells Are Modulated by Naphthalene Diimide-Like G-Quadruplex Ligands

Melanoma is the most aggressive and deadly type of skin cancer. Despite the advent of targeted therapies directed against specific oncogene mutations, melanoma remains a tumor that is very difficult to treat, and ultimately remains incurable. In the past two decades, stabilization of the non-canonic...

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Bibliographic Details
Main Authors: Marta Recagni, Martina Tassinari, Filippo Doria, Graziella Cimino-Reale, Nadia Zaffaroni, Mauro Freccero, Marco Folini, Sara N. Richter
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
<i>bcl-2</i>
g-quadruplex
<i>kit</i>
melanoma
naphthalene diimides
oncogene promoter
Online Access:https://www.mdpi.com/2073-4409/8/10/1274

Internet

https://www.mdpi.com/2073-4409/8/10/1274

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