Translation affects mRNA stability in a codon-dependent manner in human cells
mRNA translation decodes nucleotide into amino acid sequences. However, translation has also been shown to affect mRNA stability depending on codon composition in model organisms, although universality of this mechanism remains unclear. Here, using three independent approaches to measure exogenous a...
Main Authors: | Qiushuang Wu, Santiago Gerardo Medina, Gopal Kushawah, Michelle Lynn DeVore, Luciana A Castellano, Jacqelyn M Hand, Matthew Wright, Ariel Alejandro Bazzini |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/45396 |
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