Characterization of ST14A Cells for Studying Modulation of Voltage-Gated Calcium Channels.

In medium spiny neurons (MSNs) of the striatum, dopamine D2 receptors (D2Rs) specifically inhibit the Ca(v)1.3 subtype of L-type Ca(2+) channels (LTCs). MSNs are heterogeneous in their expression of dopamine receptors making the study of D2R pathways difficult in primary neurons. Here, we employed t...

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Bibliographic Details
Main Authors: Mandy L Roberts-Crowley, Ann R Rittenhouse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4492559?pdf=render