Decreased Siglec-9 Expression on Natural Killer Cell Subset Associated With Persistent HBV Replication

Decreased Siglec-9 Expression on Natural Killer Cell Subset Associated With Persistent HBV Replication

Siglec-9 is an MHC-independent inhibitory receptor selectively expressed on CD56dim NK cells. Its role in infection diseases has not been investigated yet. Here, we studied the potential regulatory roles of NK Siglec-9 in the pathogenesis of chronic hepatitis B (CHB) infection. Flow cytometry evalua...

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Bibliographic Details
Main Authors: Di Zhao, Xuemei Jiang, Yong Xu, Huimin Yang, Dongni Gao, Xueen Li, Lifen Gao, Chunhong Ma, Xiaohong Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
chronic hepatitis B
Siglec-9
NK
cytokine synthesis
cytotoxicity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01124/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01124/full

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