GAS6 receptor status is associated with dormancy and bone metastatic tumor formation.

Disseminated tumor cells (DTCs) are believed to lie dormant in the marrow before they can be activated to form metastases. How DTCs become dormant in the marrow and how dormant DTCs escape dormancy remains unclear. Recent work has shown that prostate cancer (PCa) cell lines express the growth-arrest...

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Bibliographic Details
Main Authors: Russell S Taichman, Lalit R Patel, Rachel Bedenis, Jingcheng Wang, Savannah Weidner, Taibriana Schumann, Kenji Yumoto, Janice E Berry, Yusuke Shiozawa, Kenneth J Pienta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3634826?pdf=render