Phylogeny Reconstruction with Alignment-Free Method That Corrects for Horizontal Gene Transfer.

Advances in sequencing have generated a large number of complete genomes. Traditionally, phylogenetic analysis relies on alignments of orthologs, but defining orthologs and separating them from paralogs is a complex task that may not always be suited to the large datasets of the future. An alternati...

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Bibliographic Details
Main Authors: Raquel Bromberg, Nick V Grishin, Zbyszek Otwinowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004985