Plant sterol or stanol esters retard lesion formation in LDL receptor-deficient mice independent of changes in serum plant sterols

Statins do not always decrease coronary heart disease mortality, which was speculated based on increased serum plant sterols observed during statin treatment. To evaluate plant sterol atherogenicity, we fed low density lipoprotein-receptor deficient (LDLr+/−) mice for 35 weeks with Western diets (co...

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Bibliographic Details
Main Authors: Jogchum Plat, Ilona Beugels, Marion J.J. Gijbels, Menno P.J. de Winther, Ronald P. Mensink
Format: Article
Language:English
Published: Elsevier 2006-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520432687