Nilotinib efficacy in a patient resistant to imatinib

Imatinib, a BCR-ABL inhibitor, is the standard of care for the first-line treatment of patients with chronic-phase CML. Despite the optimal results, some patients develop resistance to imatinib. For these patients, the second-generation tyrosine kinase inhibitors represent effective therapeutic opti...

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Bibliographic Details
Main Author: Luigia Luciano
Format: Article
Language:English
Published: SEEd 2015-10-01
Series:Clinical Management Issues
Subjects:
Online Access:https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/1093