Methamphetamine-induced dopamine-independent alterations in striatal gene expression in the 6-hydroxydopamine hemiparkinsonian rats.

Unilateral injections of 6-hydroxydopamine into the medial forebrain bundle are used extensively as a model of Parkinson's disease. The present experiments sought to identify genes that were affected in the dopamine (DA)-denervated striatum after 6-hydroxydopamine-induced destruction of the nig...

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Bibliographic Details
Main Authors: Jean Lud Cadet, Christie Brannock, Irina N Krasnova, Bruce Ladenheim, Michael T McCoy, Jenny Chou, Elin Lehrmann, William H Wood, Kevin G Becker, Yun Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3001483?pdf=render