Redox-responsive biocompatible nanocarriers based on novel heparosan polysaccharides for intracellular anticancer drug delivery

Heparosan is a natural precursor of heparin biosynthesis in mammals. It is stable in blood circulation but can be degraded in lysosomes, showing good biocompatibility and long circulation features. So heparosan can be designed as anticancer drug carriers to increase tumor selectivity and improve the...

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Bibliographic Details
Main Authors: Lipeng Qiu, Lu Ge, Miaomiao Long, Jing Mao, Kamel S. Ahmed, Xiaotian Shan, Huijie Zhang, Li Qin, Guozhong Lv, Jinghua Chen
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Asian Journal of Pharmaceutical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087618306688